Interchange-plus pricing passes through the wholesale interchange (set by Visa/Mastercard, paid to the card issuer) and only charges a margin on top. A typical US blended interchange is ~1.65%; a published interchange-plus margin like Helcim's 0.15-0.50% puts total cost at 1.80-2.15% on a typical mix. Flat-rate gateways (Stripe 2.9% + $0.30) hide the same stack behind one number.
Full explainer here.